Tsc1f/f
WebOverall design: p62F/F and Tsc1 F/F mice (Mori et al., 2009; Muller et al., 2013) were backcrossed to C57BL/6 mice for at least 7 generations, and then bred with Alb-Cre transgenic mice (also on C57BL/6 background) to generate p62F/F; Alb-Cre (p62Δhep) and Tsc1F/F; Alb-Cre (Tsc1Δhep)mice, respectively. p62Δhep mice were crossed to Tsc1Δhep ... Web该TSC1 Polyclonal Antibody. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
Tsc1f/f
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WebTamoxifen-injected Tsc1f/f Cre− mice (control) are shown for comparison. The γ-band of 4EBP1 represents the hyperphosphorylated form. (B) Quantification of immunoblots. WebmTORC1 is a key regulator of cell metabolism and lymphocyte proliferation. mTORC1 is inhibited by the tuberous sclerosis complex (TSC), a heterodimer of TSC1 and TSC2. Deletion of either genes results in robust activation of mTORC1. Mature B cells
WebTSC1f/f OT1 and mice mice had been extracted from The Jackson Lab, while Compact disc4Cre mice had been extracted from Taconic Farms. Mice had been housed under specific-pathogen-free circumstances and found in compliance with Country wide Institutes of Health guidelines. WebE, the brain tissues from WT mice, Tsc1f/f Syn1Cre mice, and Tsc1f/f Syn1Cre mice treated with rapamycin (R) (Tsc1f/f Syn1Cre +R) were immunoblotted. F, HepG2, Bel-7402, SK-HEP-1, A549, and ELT3 cells were treated with or without 10 n m rapamycin (R) for 24 h and then subjected to immunoblotting.
WebJan 12, 2024 · CD11c Cre, Tsc1 f/f, Raptor f/f, OT-I and OT-II mice were purchased from Jackson Laboratories (Bar Harbor, ME, USA). All used mice have been backcrossed with … WebTSC1-conditional knockout (DMP1-Cre+ ; TSC1f/f , hereafter CKO) mice and littermate control (DMP1-Cre- ; TSC1f/f , hereafter WT) mice were generated. H&E staining, …
WebThe resultant conditional Tsc1f/f;Cre⫹/⫺ an- which time, whole body and organ specific FDG uptake imals (designated as Tsc1c⫺/⫺) were viable and fertile was quantified. Results were based on the ratio of FDG Figure 6. Liver-specific activation of mTORC1 in Tsc1c⫺/⫺ mice.
WebPurchase TSC1F Plumbing Material for Water Supply, ESLON Fitting, "HI-TS / Gold / TS / HI Transparent Blue" Cap from SEKISUI CHEMICAL and many other industrial components. … incitec pivot pty ltdWebWe allowed Tsc1f/f; Rosa26-CreERT2 glioma cells to form spheres in culture and then added 4-hydroxytamoxifen (4-OHT) to delete the Tsc1 gene. First, we confirmed that 4-OHT efficiently induced Tsc1 deletion in these sphere cells, as evidenced by the disappearance of TSC1 protein from lysates of sphere cells that had been cultured with 4-OHT ( Fig. 2 A ). incitec pivot waggamanWeb153. Maira S, Stauffer F, Brueggen J, Furet P, Schnell C, Fritsch C, et al. Identification and char-acterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/ mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Mol Cancer Ther 2008; 7:1851-63. 154. incitec pivot smithtonWebFeb 1, 2024 · TSC1-conditional knockout (DMP1-Cre+ ; TSC1f/f , hereafter CKO) mice and littermate control (DMP1-Cre- ; TSC1f/f , hereafter WT) mice were generated. H&E … incitec pivot share price forecastWebCatalogue Number 160865: Antigen/Gene or Protein Targets Tsc1/Hamartin incitec pivot south australiaWebNCBI's Gene Expression Omnibus (GEO) is a public archive and resource for gene expression data. incitec pivot salaryWebMay 30, 2013 · Caroline F. Bruinsma MSc. Department of Neuroscience, Erasmus University Medical Center, Rotterdam, the Netherlands. ENCORE Expertise Center for … incitec pivot wiki