WebParthenolide inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml). Parthenolide also induces apoptosis in cancer cells, at least in part by inhibiting … WebParthenolide is a sesquiterpene lactone of the germacranolide class which occurs naturally in the plant feverfew (Tanacetum parthenium), after which it is named, and in the closely …
Anticancer and apoptotic activities of parthenolide in
WebAntimonials continue to be considered the first-line treatment for leishmaniases, but its use entails a wide range of side effects and serious reactions. The search of new drugs requires the development of methods more sensitive and faster than the conventional ones. We developed and validated a fluorescence assay based in the expression of tdTomato … Web7 Oct 2014 · At the IC 50 of parthenolide, the p53 gene mRNA relative band intensity increased by 9.67- and 3.15-fold in SiHa and MCF-7 cells, respectively. Similarly, … children\u0027s table and 4 chair set
IC50 - Wikipedia
Web6 Feb 2024 · Dr. Morahem Ashengroph received a B.Sc. degree in General Microbiology from the University of Isfahan, Iran in 2001, a M.Sc. degree in Environmental Microbiology (2005) under the supervision of Prof. Fereydoun Malekzadeh from the University of Tehran, Iran and a Ph.D. (2010) in Industrial Microbiology under the supervision of Prof. Iraj Nahvi from the … WebRomidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin … WebParthenolide is a sesquiterpene lactone present abundantly in the leaves and flowers of Tanacetum parthenium. [ 4] It exhibits anti-cancer properties for the treatment of invasive … go winthrop