Pac1 cell line
WebJul 29, 2024 · Here, we report the establishment of a pro-acinar (mSG-PAC1) and ductal (mSG-DUC1) cell line, from the murine submandibular salivary gland (SMG), which recapitulate developmental milestones in differentiation. mSG-DUC1 cells express the ductal markers, keratin-7 and keratin-19, and form lumenized spheroids. mSG-PAC1 … WebApr 3, 2003 · To determine the role of PAC1 in the apoptotic process, a human PAC1 expression vector, pcDNA3-PAC1, was transfected into EB cells and a breast cancer cell line, MDA-MB435, which were then ...
Pac1 cell line
Did you know?
WebMethod for producing an adapted virus population from an African green monkey kidney cell line 摘要 The invention described herein provides a method for selecting a novel African Green monkey kidney (AGMK) cell substrate, its cultivation and serial passage and its subsequent characterization. The invention provides a method for the use of the ... WebMillipore’s cloned human PAC1-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant PAC1 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists ...
WebWe compared these results to responses in a recombinant CHO-PAC1 cell line, chosen because the CHO cell background is one of those most commonly used for screening despite bearing little similarity to the neuronal cells it is being asked to model, and thus illustrating how cellular background can affect signaling responses. PAC1 (pituitary ... WebJul 29, 2024 · Here, we report the establishment of a pro-acinar (mSG-PAC1) and ductal (mSG-DUC1) cell line, from the murine submandibular salivary gland (SMG), which …
WebMethod for producing an adapted virus population from an African green monkey kidney cell line 要約 The invention described herein provides a method for selecting a novel African Green monkey kidney (AGMK) cell substrate, its cultivation and serial passage and its subsequent characterization. The invention provides a method for the use of the ... WebDiscoverX offers over a decade of experience in generating stable cell lines of unsurpassed quality and leading performance utilizing the proprietary enzyme fragment complementation (EFC) technology against a broad range of target classes (GPCRs, kinases, epigenetics targets (methyltransferases, bromodomains), interleukins, NHRs, pathways and more). …
WebMultiscreen™ Stable Cell Line - Vasoactive Intestinal Peptide Family PAC1 receptor. View product information for catalog number - C1415. Downloadable pdf data sheet available. ... The pituitary adenylate cyclase-activating polypeptide (PACAP)- selective PAC1 receptor (PAC1R, ADCYAP1R1) is a member of the vasoactive intestinal peptide (VIP ...
WebThe green fluorescent PAC1 receptor cell line allows compounds to be tested or analyzed for their ability to modulate PAC1 receptor activation and the following redistribution processes within the cell. When the ligand binds to the PAC1 receptor, it activates the G protein, which is internalized in large, high-strength vesicles. twin falls nwtWebcompared the PAC1 cells to a highly transducible lung cancer cell line. Using Ad-RSV-beta-gal as a control vector, we transduced H1299 NSCLC cells with an efficiency sim-ilar to that of PAC1 cells. However, PAC1 cells were trans-duced 10-fold more efficiently than H1299 cells after treatment with Ad-SM22-beta-gal (Fig. 1). Comparably twin falls non denominational churchesWebThe GeneBLAzer™ PAC1-CRE-bla CHO-K1 cells contain the human Adenylate Cyclase Activating Polypeptide 1 Receptor 1 (ADCYAP1R/PAC1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat #K1129) contain a beta-lactamase (bla) reporter gene under control of the cAMP response … twin falls parcel searchWebVascular endothelial cell injury and resultant endothelial dysfunction seems to play a key role in the prothrombotic ... (p=0.56). Baseline (p=0.001) and ADP-stimulated (p=0.003) PAC1 binding was significantly higher in Behçet’s patients than in the con-trol group. Clinical activity has no effect on P-selectin expression and PAC1 binding ... twin falls north bendWebPAC1 Receptor Cell Line contains HEK293 cells stably expressing PAC1R with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell … twin falls north bend waWebNational Center for Biotechnology Information twin falls new yorkWebPSMG1 (PAC1) functions in a heterodimeric complex with PSMG2 (PAC2) and was originally identified as a proteasome subunit binding partner (4). Intact PSMG1-PSMG2 heterodimers both promote heteroheptameric α-ring assembly and/or stability and prevent accumulation of non-productive α-ring dimers (4). twin falls of richland ar