Fermitin family homolog 3
WebProtein 3 DNA Repair Enzymes AlkB Enzymes AlkB Homolog 1, Histone H2a Dioxygenase AlkB Homolog 2, Alpha- ... Databases HGMD ClinVar FERMT1 20p12 .3 Fermitin family homolog 1 FERMT1 database FERMT1 FERMT1 Data are compiled ... is well conserved throughout evolution with closely related homologs in Drosophila and Caenorhabditis … WebJun 1, 2016 · Select the department you want to search in ...
Fermitin family homolog 3
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WebSep 26, 2024 · fermitin family homolog 3, unc-112-related protein 2 GeneRIFs: Gene References Into Functions Kindlin-3 maintains marginal zone B cells but confines follicular B cell activation and differentiation. Low kindlin-3 levels in osteoclasts of kindlin-3 hypomorphic mice result in osteopetrosis due to leaky sealing zones. Fermitin family homolog 3) (FERMT3), also known as kindlin-3 (KIND3), MIG2-like protein (MIG2B), or unc-112-related protein 2 (URP2) is a protein that in humans is encoded by the FERMT3 gene. The kindlin family of proteins, member of the B4.1 superfamily, comprises three conserved protein homologues, … See more It has been suggested that the evolutionary source of a single ancestral Kindlin protein is the earliest metazoa, the Parazoa. Within vertebrates, these ancestral proteins were subjected to duplication … See more FERMT3 mutations can result in autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). a deficiency in beta1, beta2 and beta3 integrin activation in platelets and leukocytes that causes haemorrhaging and recurrent … See more The FERMT3 protein has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Kindlin 3 is a cytoskeletal signalling protein involved in the activation of the glycoprotein … See more • Etzioni A (October 2009). "Genetic etiologies of leukocyte adhesion defects". Current Opinion in Immunology. 21 (5): 481–6. See more
WebEarly History of the Fermin family. This web page shows only a small excerpt of our Fermin research. Another 59 words (4 lines of text) covering the years 1937, 1614, 1697, 1662, … WebFERMT3 (Fermitin family homolog 3; also kindling-3, MIG2B and URP2) is a 72-78 kDa member of the kindling family of proteins. It is a cytoplasmic protein that is expressed by B cells, T cells, platelets, neutrophils and vascular endothelial cells. FERMT3 acts on the cytoplasmic tails of beta -integrins 1 thru 3 to induce a conformational change ...
WebFermitin family homolog 3 Protein also known as : Unc-112-related protein 2 . Gene name : FERMT3; Family name : Kindlin Protein Recommended name Fermitin family homolog 3 Alternative names WebSep 10, 2024 · Fermitin family homolog 3 TASGDYIDSSWELR 4 Y11 P04075 ALDOA Fructose-bisphosphate aldolase A GILAADESTGSIAKR 4 S36 H0YJ30 GPHN Gephyrin ASHSAVDITK 4 S303/S305 Q2Q9B7 G6PD Glucose-6-phosphate 1-dehydrogenase VQPNEAVYTK 4 Y401 E9PK89 RAB3IL1 Guanine nucleotide exchange factor for Rab …
WebApr 12, 2024 · ABSTRACT. Alterations of cell mechano-environment and metabolism are common features of malignant neoplasm. We recently showed that increased stiffness of extracellular matrix is intrinsically linked to up-regulation of proline synthesis through a mechano-responsive fermitin family homolog 2 (FERMT2, best known as kindlin-2) … the illahie foundationWebIn a highly inbred Australian Shepherd litter, three of the five puppies developed widespread ulcers of the skin, footpads, and oral mucosa within the first weeks of life. Histopathological examinations demonstrated clefting of the epidermis from the underlying dermis within or just below the basement membrane, which led to a tentative diagnosis of junctional … the illager raid legoWebThis study provides evidence that fermitin family homolog-1 is implicated in integrin activation and demonstrates that lack of this protein leads to pathological changes beyond focal adhesions, with disruption of several hemidesmosomal components and reduced expression of keratinocyte stem cell markers. the illative senseWebAlternative name4. UNC-112 related protein 2. Alternative name5. Anti -UNC-112 related protein 2 (fermitin family homolog 3, KIND3, Kindlin-3, MGC10966, MIG-2, MIG2B, MIG2-like, UNC112C,, Unc-112-related protein 2, URP2, URP2SF) Other names. UNC-112 related protein 2, isoform CRA_b; Fermitin family homolog 3; fermitin family homolog 3; … the illation groupWebFermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans is encoded by … the illawarra connectionWebfermitin family homolog 2 (Drosophila) Calculated MW: 680 aa, 78 kDa Observed MW: 78 kDa Purification Method: Antigen affinity purification Recommended Dilutions: WB 1:2000-1:12000 IHC 1:50-1:500 Applications Tested Applications: ... PBS with 0.02% sodium azide and 50% glycerol pH 7.3. the illapa projectWebfermitin family homolog 2 (Drosophila) Calculated molecular weight: 680 aa, 78 kDa: Observed molecular weight: 78 kDa: GenBank accession number: BC017327: Gene symbol: ... Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary … the illawarra